A majority of United States Senators voted 68-29 to confirm the nomination of Mayor Martin Walsh as the US Secretary of Labor this afternoon.
Among those who voted for Walsh from the GOP ranks were Sen. Mitt Romney, Sen. Susan Collins and Sen.Lindsay Graham.
He will resign via a letter to the City Clerk tonight at 9 p.m., according to Walsh, an action that will elevate City Council President Kim Janey to the role of acting Mayor. He will go to the nation's capitol on Tuesday to be sworn-in.
Janey is expected to be inaugurated during a ceremony on Wednesday.
Walsh, 53, a Dorchester resident and past union leader, breezed through his committee hearing on Feb. 4 and the Senate Committee on Health, Education, Labor and Pensions voted 18-4 to "report favorable" on Walsh's nomination a week later.
Janey will make history when she becomes the first Black and first female Boston mayor. She has not yet declared a candidacy to seek a four-year term in this year's election.