The John F. Kennedy Presidential Library and Museum will host a five-day celebration over Memorial Day weekend to mark the slain president’s 100th birthday. John F. Kennedy, who was born in Brookline and had deep maternal ties to Dorchester, would have turned a centenarian on the holiday, May 29.

Beginning on Thursday (May 25), the festivities will include the opening of new exhibition “JFK100: Milestones & Mementos,” a forum featuring the historian David McCullough, and family-friendly activities with a NASA astronaut and spacesuit engineer. On May 29, admission to the museum, which charges $14 each to adults, with discounts for other categories, will be free and open to the public all day.

The exhibit will open to the public on Friday at 11 a.m. and remain on display through May of next year. It features 100 original artifacts, ranging from his mother’s notes about Jack’s childhood health to JFK’s undelivered remarks prepared for the Dallas Citizens Council on Nov. 22, 1963.

Friday will see a family-friendly afternoon, bringing President Kennedy’s Space Race legacy up to the modern era. In addition to hands-on activities and games, attendees will hear from NASA astronaut Christopher Cassidy and spacesuit engineer Su Curley.

The daylong birthday celebration on Monday will feature performances by the US Navy Band, the Boston City Singers, a ceremonial cake cutting, and a Navy flyover.

See jfklibrary.org for a full schedule.